GASTROSCAN M 30
Mannitol Solution
As Negative Contrast
ADVANTAGES:
✔ Excellent Image Quality due to long Duration of Action (4 to 6 hours).
✔ Effective Distension.
✔ Appealing Palatability.
✔ Eliminates the need to administer rectal contrast media.
✔ No Discomfort To Patient.
✔ Mannitol possessing extra osmotic properties provides extra beneficial effects in cases of Brain injury.
Axial CT scan oral administration of Gastroscan M 30 and IV contrast demonstrating excellent distention of small bowel loopswith muscosal enhancement & bowel wall thickening due to Crohn's disease.
Coronal MDCT Image with natural contrast against Gastroscan M 30 demonstrating excellent distension of small bowel loops.
Axial CT Image demon-strates focal enhancing lesion is duodenum representing a carcinoid with metastases to the liver.
Curved MRP demonstrating mucosal enhancement of a segment of small bowel due to Crohn's disease.
LIMITATIONS OF POSITIVE ENTERAL CONTRAST:
✔ Limits evaluation of mucosal and sub-mucosal enhancement pattern seen in inflammatory bowel disease as well as hyper-vascular bowel tumors like GIST/CARCINOID.
✔ Limits evaluation of gastrointestinal haemorrhage.
✔ Interferes in post processing of mesenteric vessels.
A) Comparative table for qualitative analysis of overall bowel distension, fold visibility and Intraluminal homogeneity.
| Distension (%) | Fold Visibility (%) | Intraluminal Homogeneity (%) | |||||||
| Fair | Good | Excellent | Fair | Good | Excellent | Fair | Good | Excellent | |
|---|---|---|---|---|---|---|---|---|---|
| Mannitol | 10 | 64 | 26 | 8 | 58 | 34 | 6 | 63 | 31 |
| Positive | 58 | 36 | 8 | 43 | 57 | 0 | 37 | 52 | 11 |
| Water | 49 | 51 | 0 | 56 | 44 | 0 | 55 | 45 | 0 |
B) Quantitative comparison of mean distension (in centimeters with two standard deviation) of bowel loops at various levels :
| Stomach | Pylorus | D2 | D3 | Jejunum | Ileum | IC junction | |
|---|---|---|---|---|---|---|---|
| Mannitol | 8.4+1.20 | 3.37+0.67 | 1.84+0.39 | 1.66+0.34 | 1.93+0.36 | 2.11+0.25 | 1.42+0.45 |
| Positive | 7.8+0.96 | 3.17+0.62 | 1.83+0.35 | 1.64+0.28 | 1.70+0.34 | 1.71+0.23 | 1.34+0.52 |
| Water | 7.5+1.0 | 3.11+0.59 | 1.81+0.41 | 1.62+0.31 | 1.60+0.46 | 1.62+0.23 | 1.16+0.36 |
C) Quantitative comparison of fold visibility in IC junction.
| Grade 0 (%) | Grade I (%) | Grade II (%) | |
|---|---|---|---|
| Mannitol | 10 | 19 | 71 |
| Positive | 34 | 31 | 35 |
| Water | 52 | 35 | 13 |
| IC : Ileo-caecal |
D) Quantitative comparison of fold visibility in ileum
| Grade II (%) | Grade II (%) | Grade II (%) | |
|---|---|---|---|
| Mannitol | 0 | 12 | 88 |
| Positive | 0 | 34 | 66 |
| Water | 17 | 40 | 43 |
E) Quantitative comparison of fold visibility in jejunum
| Grade II (%) | Grade II (%) | Grade II (%) | |
|---|---|---|---|
| Mannitol | 10 | 28 | 62 |
| Positive | 18 | 48 | 34 |
| Water | 18 | 43 | 39 |
lleo-caecal Region Distension
lleo-caecal region distension obtained was comparable between Mannitol.
Iodinated contrast.
Poor with Water.
Also, note the good large bowel distension achieved with Mannitol.
Duodenal Distension
Similar degree of duodenal distension achieved with 3% Mannitol.
Iodinated contrast.
Water without any additives.
CONTRAINDICATIONS:
Hypersensitivity to Mannitol Solution.
STORAGE:
Store in cool & dry place away from sunlight.
Do not freeze. Protect from secondary radiation.
Single dose for one patient.
Discard unused portion.
Keep away from reach of children.
PRESENTATION:
100 ml Pet-Bottle.
